Thus a lack of basic science review and the perpetuation of clinical pain management practices that do not effectively control acute or chronic pain results this book tries to provide basic information about pain and recommendations for rational pain treatment with medications. Full text full text is available as a scanned copy of the original print version get a printable copy pdf file of the complete article 188k or click on a page image below to browse page by page. Carbamazepine tegretol is the most widely studied aed and demonstrates effective treatment of neuropathic pain 24 aeds have many other pharmacological actions that may produce analgesia thus making them potential treatments for a variety of chronic pain conditions unfortunately use of carbamazepine is limited by intolerable side effects . These guidelines are summarized in table 1 1 3 for cancer pain the selection of an analgesic is based on pain severity 2 guidelines on the use of opioids for chronic noncancer pain stress the importance of patient evaluation and selection before initiation of opioids to determine the suitability of opioid analgesics 13 when needed opioid . A wide range of drugs is used to manage pain resulting from inflammation in response to tissue damage chemical agents pathogens nociceptive pain or nerve damage neuropathic pain most drugs act by binding to protein targets on cell membranes and affecting the biochemical processes of the body protein targets are specific to specific tissues allowing drugs to be precisely targeted at
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